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Efficacy of a Community Dengue Early-warning Programme in Urban Dhaka

BDCTR ID
BDCTR-2026-000142
Sponsor
Bangladesh Medical University
Information provided by
Dr Farhana Islam, Associate Professor (Responsible Party)
Last Update Posted
2026-10-01

Study Overview

Brief Summary

This study tests whether a neighbourhood early-warning and vector-control programme reduces laboratory-confirmed dengue incidence during the monsoon season in dense urban wards of Dhaka.

Detailed Description

Wards are randomised to the intervention or usual care. The intervention combines weekly larval surveillance, community alerts, and targeted source reduction. Incidence is tracked through sentinel clinics and laboratory confirmation over one transmission season.

Official Title

A Cluster-randomised Trial of a Community Early-warning and Vector-control Programme to Reduce Dengue Incidence in Dense Urban Wards of Dhaka

Conditions

  • Dengue Fever
  • Vector-borne Diseases

Intervention/Treatment

  • Behavioral: Community early-warning and vector-control programme

Other Study ID Numbers

BMU-MED-2026-014

Study Start

2026-10-15

Primary Completion

2027-06-30

Study Completion

2027-09-30

Enrollment (Estimated)

4,200

Study Type

Interventional

Phase

N/A

Contacts and Locations

This section provides contact details for people who can answer questions about joining this study, and information on where this study is taking place.

To learn more, please see the Contacts and Locations section in How to Read a Study Record.

Study Contact

Name: Dr Farhana Islam

Phone Number: +8802550000142

Email: dengue-study@bmu.ac.bd

This study has 1 location

Bangladesh

  • Dhaka, Dhaka, Bangladesh, 1000

    Recruiting

    Faculty of Medicine, Bangladesh Medical University

    Contact: Dr Farhana Islam

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

<p>Inclusion Criteria:</p><ul><li>Resident of a participating urban ward.</li><li>Household agrees to periodic surveillance visits.</li></ul><p>Exclusion Criteria:</p><ul><li>Planned relocation within the study period.</li></ul>

Ages Eligible for Study

All ages (Child, Adult, Older Adult)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

Yes

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Primary Purpose:
Prevention
Allocation:
Randomized
Interventional Model:
Parallel Assignment
Masking:
Single blind

Arms and Interventions

Participant Group/ArmIntervention/Treatment

Experimental: Early-warning programme

Weekly surveillance, community alerts, and targeted source reduction.

Behavioral: Community early-warning and vector-control programme

Surveillance, alerts, and source reduction delivered at ward level.

No Intervention: Usual care

Standard municipal vector-control activities.

What is the study measuring?

Primary Outcome Measures

Outcome MeasureMeasure DescriptionTime Frame
Laboratory-confirmed dengue incidence per 1,000 residentsConfirmed cases recorded through sentinel clinics.6 months

Secondary Outcome Measures

Outcome MeasureMeasure DescriptionTime Frame
Household larval indexMonthly to 6 months
Time from alert to source-reduction actionThrough study completion, 6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Bangladesh Medical University

Collaborators

Directorate General of Health Services

Study Record Dates

These dates track the progress of study record and summary results submissions to the registry. Study records and reported results are reviewed by the Registry Office to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted that Met QC Criteria

2026-09-28

First Posted

2026-09-28

Study Record Updates

Last Update Submitted that Met QC Criteria

2026-10-01

Last Update Posted

2026-10-01

Last Verified

2026-09

More Information

Record History

Terms related to this study

Keywords Provided by Bangladesh Medical University

  • dengue
  • vector control
  • early warning
  • urban health

Plan for Individual Participant Data (IPD)

Plan to Share Individual Participant Data (IPD)?

Not provided

Drug and device information, study documents, and helpful links

Data Monitoring Committee

Yes